肌钙蛋白检测

定义

A troponin test measures the levels of troponin T or troponin I proteins in the blood. These proteins are released when the heart muscle has been damaged, 比如心脏病发作时. 对心脏的伤害就越大, the greater the amount of troponin T and I there will be in the blood.

选择的名字

TroponinI; TnI; TroponinT; TnT; Cardiac-specific troponin I; Cardiac-specific troponin T; cTnl; cTnT

如何执行测试

A 血液样本 是必要的.

如何准备考试

No special steps are needed to prepare, most of the time.

考试的感觉如何

You may feel slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn.

为什么要进行测试

The most common reason to perform this test is to see if a heart attack has occurred. Your health care provider will order this test if you have chest pain and other signs of a heart attack. The test is usually repeated two more times over the next 6 to 24 hours.

Your provider may also order this test if you have 心绞痛 that is getting worse, but no other signs of a heart attack. (Angina is chest pain thought to be from a part of your heart not getting enough blood flow.)

The troponin test may also be done to help detect and evaluate other causes of heart injury.

The test may be done along with other cardiac marker tests, such as 肌酸磷酸激酶同功酶 or 肌红蛋白.

正常的结果

Cardiac troponin levels are normally so low they cannot be detected with most blood tests.

Having normal troponin levels 12 hours after chest pain has started means a heart attack is unlikely.

A normal value range may vary slightly among different laboratories. Some labs use different measurements (for example, "high sensitivity troponin test") or test different samples. Also, some labs have different cutoff points for "normal" and "probable myocardial infarction." Talk to your provider about the meaning of your specific test results.

异常结果意味着什么

Even a slight increase in the troponin level will often mean there has been some damage to the heart. Very high levels of troponin are a sign that a heart attack has occurred.

Most patients who have had a heart attack have increased troponin levels within 6 hours. After 12 hours, almost everyone who has had a heart attack will have raised levels.

Troponin levels may remain high for 1 to 2 weeks after a heart attack.

Increased troponin levels may also be due to:

• 心跳异常快
• 肺动脉高血压(肺动脉高压)
• Blockage of a lung artery by a blood clot, fat, or tumor cells (肺栓塞物)
• 充血性心力衰竭
• 冠状动脉痉挛
• Inflammation of the heart muscle usually due to a virus (心肌炎)
• Prolonged exercise (for example, due to marathons or triathlons)
• Trauma that injures the heart, such as a car accident
• 心肌的衰弱(心肌病)
• 长期肾病

Increased troponin levels may also result from certain medical procedures such as:

• 心脏血管成形术和支架植入
• 心脏除颤或 电复律法 (purposeful shocking of the heart by medical personnel to correct an abnormal heart rhythm)
• 心脏直视手术
• 心脏的射频消融

参考文献

Bohula EA, Morrow DA. ST-Elevation myocardial infarction: management. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12日艾德. Philadelphia, PA: Elsevier; 2022:chap 38.

Bonaca MP, Sabatine MS. 接近胸痛病人. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12日艾德. Philadelphia, PA: Elsevier; 2022:chap 35.

Levine GN, Bates ER, Blankenship JC，等. 2015 ACC/AHA/SCAI Focused update on primary percutaneous coronary intervention for patients with ST-Elevation myocardial infarction: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines and the Society for Cardiovascular Angiography and Interventions. 循环. 2016;133(11):1135-1147. PMID: 26490017 pubmed.ncbi.nlm.国家卫生研究院.gov / 26490017 /.

Thygesen K, 阿尔珀特JS, 杰夫,, Chaitman BR, Bax JJ; Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal 定义 of Myocardial Infarction. Fourth Universal 定义 of Myocardial Infarction (2018). 循环. 2018;138(20):e618-e651 PMID: 30571511 pubmed.ncbi.nlm.国家卫生研究院.gov / 30571511 /.